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Product Description
Glucophage is an oral medication used to manage type 2 diabetes. Its active ingredient, metformin, belongs to a class of drugs called biguanides. It works by reducing the concentration of glucose (sugar) in the blood through several mechanisms:
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Suppressing glucose production in the liver
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Reducing glucose absorption from the gastrointestinal tract
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Improving glucose utilization in tissues
One of the key benefits of Glucophage is that it can help stabilize or even reduce body weight in people with type 2 diabetes. Importantly, the medication does not cause hypoglycemia (low blood sugar) when taken as directed. It also improves the blood’s fibrinolytic properties, which help break down blood clots.
Glucophage is often prescribed when other treatments, such as sulfonylureas, have been ineffective, especially in patients with obesity.
It is important to only take Glucophage if it has been prescribed by your doctor and to not exceed the recommended dose. The medication is typically taken with meals unless your healthcare provider instructs you otherwise.
Glucophage is usually taken in 500 mg or 850 mg doses twice a day to treat type 2 diabetes in adults. Based on your blood sugar levels, your doctor may adjust the dose, with the maximum daily dose being 2550 mg, taken in three divided doses.
Serious Side Effects
In rare cases, Glucophage can cause a potentially life-threatening condition known as lactic acidosis. Symptoms of this condition include:
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Weakness
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Increased drowsiness
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Slow heartbeats
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Feeling cold
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Muscle pain
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Abdominal pain
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Difficulty breathing
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Fainting or dizziness
If you experience any of these symptoms, seek immediate medical attention. Also, be aware of the signs of low blood sugar, such as hunger, confusion, irritability, drowsiness, headache, weakness, rapid heartbeats, tremors, sweating, and seizures. Always keep a source of sugar (such as glucose tablets or fruit juice) nearby.
Contraindications and Warnings
Glucophage should not be used if you have:
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Hypersensitivity (allergic reactions) to metformin or any of its ingredients
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Diabetic coma, ketoacidosis, or hyperglycemic coma
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Kidney problems or liver disease
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Heart failure, recent heart attack, or respiratory failure
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Dehydration, infections, or have undergone major surgery or trauma
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Chronic alcohol use or a very low-calorie diet (less than 1000 kcal/day)
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Pregnancy or breastfeeding
Glucophage is not recommended for individuals over the age of 60 who engage in intense physical labor, as this increases the risk of lactic acidosis.
Additionally, Glucophage should be avoided for two days before certain medical procedures, such as surgery, radioisotope tests, or CT scans that involve contrast agents.
Overdose and Symptoms
An overdose of Glucophage may cause symptoms of low blood sugar (hypoglycemia), such as hunger, confusion, irritability, drowsiness, headache, weakness, tremors, sweating, and rapid heartbeats. If you experience any of these symptoms, contact your healthcare provider immediately.
Conditions Treated by Glucophage
Type 2 Diabetes: This condition occurs when the body either does not produce enough insulin or becomes resistant to the insulin it produces. Insulin is necessary for regulating blood sugar levels. Glucophage helps control blood sugar by improving insulin sensitivity and decreasing glucose production in the liver.
In addition, Glucophage is sometimes used to treat other conditions, such as polycystic ovary syndrome (PCOS), where it helps to regulate insulin levels and may assist with weight loss and ovulation in women with this condition.
Explore these other products in this category: GLUCOVANCE and STARLIX.
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