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Product Description
Glucophage SR (Sustained Release) is an oral medication primarily used to manage type 2 diabetes. Its active ingredient, metformin, belongs to a group of drugs called biguanides. Metformin works by lowering blood sugar levels in several ways: it reduces the production of glucose (sugar) in the liver, decreases the absorption of sugar from the digestive tract, and helps your body use insulin more effectively.
One of the key benefits of Glucophag
e is that it helps stabilize or even reduce body weight, which is especially useful for diabetic patients who are overweight. Importantly, this medication does not cause hypoglycemia (dangerously low blood sugar) when used alone.
Glucophage is prescribed to adults with type 2 diabetes, including those who have not responded well to other treatments such as sulfonylureas. It is especially recommended for individuals with obesity-related diabetes.
Common Diseases Treated
Glucophage SR is mainly used to treat type 2 diabetes mellitus, a chronic condition in which the body either resists the effects of insulin or doesn’t produce enough insulin to maintain normal blood sugar levels. Uncontrolled diabetes can lead to severe complications such as heart disease, nerve damage, kidney failure, and vision problems.
How to Use
Always take Glucophage SR exactly as prescribed by your doctor. It’s typically taken once or twice daily with meals to reduce the chance of stomach upset. The usual starting dose is 500 mg or 850 mg per day, but based on your blood sugar response, your doctor may gradually increase your dosage up to a maximum of 2550 mg per day, split into multiple doses.
Never take more than the recommended dose, and do not take it without a doctor’s prescription.
Important Safety Information
This medication is not suitable for everyone. Do not use Glucophage if you have:
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Severe kidney or liver problems
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Heart failure or a recent heart attack
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Serious infections, dehydration, or severe trauma
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A history of lactic acidosis (a rare but serious complication where lactic acid builds up in the blood)
Glucophage should also be stopped temporarily before surgeries or certain medical exams like X-rays or CT scans that use contrast dye, as this can raise the risk of kidney problems.
Potential Side Effects
Common side effects may include:
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Nausea
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Diarrhea
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Bloating
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Gas
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Loss of appetite
More serious side effects to watch for include signs of lactic acidosis, which can be life-threatening. Symptoms include extreme weakness, unusual drowsiness, slow or irregular heartbeat, muscle pain, stomach discomfort, trouble breathing, and feeling faint. If you experience any of these, seek medical help immediately.
Although rare, allergic reactions may occur, with symptoms like rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, and trouble breathing.
Drug Interactions
Glucophage can interact with other medications. For example:
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Cimetidine (Tagamet) can increase metformin levels in your blood.
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Alcohol use increases the risk of lactic acidosis.
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Some medications, such as diuretics, steroids, thyroid drugs, and birth control pills, can reduce the effect of Glucophage.
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Other drugs like insulin and sulfonylureas may enhance its blood sugar-lowering effect.
Always inform your doctor of all medications, supplements, and herbal products you are taking.
Overdose
Signs of an overdose include symptoms of low blood sugar, such as hunger, confusion, drowsiness, headache, rapid heartbeat, shakiness, and sweating. More severe cases can lead to lactic acidosis, requiring immediate medical attention.
Other Medications in This Category
Other popular drugs for type 2 diabetes include GLUCOTROL XL and MICRONASE.
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